WebAug 4, 2006 · Results suggest that both TaI and TaL PKSs might act in conjunction with a methyltransferase, reductases, and a monooxygenase to produce the 2‐hydroxyvaleryl–S–ACP starter that is proposed to act as the biosynthetic primer in the initial condensation reaction with glycine. Myxococcus xanthus DK1622 is shown to be a … WebApr 14, 2014 · For example, expression of genes for the yellow pigment DKxanthene and the antibiotic myxovirescin was increased significantly in yellow variants. In contrast, expression of the siderophore myxochelin, hemin binding proteins, and iron transport proteins was increased specifically in tan strains. Thus, a consequence of phase …
The unique DKxanthene secondary metabolite family …
WebRolf Müller, R. Müller, 2004, Journal of Cancer Research and Clinical Oncology. WebFigure 4: Structures of DKxanthene-534 and myxochelin A. Halotolerant and halophilic marine myxobacteria are poorly in-vestigated regarding secondary metabolite production. There-fore, the pool of secondary metabolites isolated from organisms of this kind is very low to date, when compared to that of their terrestrial counterparts. giovanni kelly waynesboro
DKxanthene Biosynthesis—Understanding the Basis for …
WebNov 4, 2024 · The screened strongest constitutive promoter was used to efficiently enhance the expression of two complex BGCs governing the biosynthesis of myxochromide and DKxanthene in the model myxobacterium ... WebRegarding DKxanthene, in DK1622hsfA::kan production is decreased 7-fold, which is not the case on solid CTT-agar. In the case of myxovirescin, the amount is decreased 3-fold compared to the wild-type instead of an increase observed when grown on CTT-agar. However, myxochromide exhibited changes compared to the wild-type as seen before on … http://www.nlm.medscape.idmu.unboundmedicine.unboundmedicine.com/medline/citation/18721748/DKxanthene_biosynthesis__understanding_the_basis_for_diversity_oriented_synthesis_in_myxobacterial_secondary_metabolism_ fulmer library sheridan wy